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H-Trimazole 10 gm Cream
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The treatment of fungal infections where co-existing symptoms of inflammation e.g. itching, require rapid relief.
- All dermatomycoses due to dermatophytes (e.g. Trichophyton species), moulds and other fungi.
- All dermatomycoses due to yeasts (Candida species).
- Skin diseases showing secondary infection with these fungi
- The treatment of nappy rash where infection due to Candida albicans is present.
Hydrocortisone & Combined preparations
Clotrimazole inhibits ergosterol synthesis, which leads to structural and functional impairment of fungal cytoplasmic membrane. Hydrocortisone, a weak corticosteroid with both glucocorticoid and to a lesser extent mineralocorticoid activity, has antiphlogistic, antipruriginous, antiexudative and antiallergic effects.
Dosage & Administration
Apply thinly and evenly to the affected area twice daily
May reduce effectiveness of contraceptives.
It is contraindicated in patients with known hypersensitivity to any of the components of this preparation.
Allergic reaction (e.g. syncope, urticaria, dyspnoea, hypotension), blisters, oedema, discomfort/ pain, erythema, peeling/ exfoliation, irritation. Rarely, hypothalamic-pituitary adrenal axis suppression, cushingoid features, delayed wt gain/ growth retardation in childn, glaucoma, HTN, hyperglycaemia/ glucosuria, osteoporosis, cataract, increased wt/ obesity, decreased endogenous cortisol levels, steroid withdrawal syndrome.
Pregnancy & Lactation
Pregnancy category: Not Classified. FDA has not yet classified the drug into a specified pregnancy category.
Precautions & Warnings
In infants, the napkins may act as an occlusive dressing and increase absorption. Treatment should be for a maximum period of seven days.
Rarely local mild burning or irritation may be experienced. Hypersensitivity reactions may occur
Store below 25°C.
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