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Orbidex G Ophthalmic Solution Gatifloxacin + Dexamethasone 0.3%+0.1% – 5 ml drop
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This Sterile Eye Drops is indicated for steroid responsive ocular inflammatory conditions with involvement of bacteria like blepharitis, scleritis, episcleritis, iritis, cyclitis, iridocyclitis, choroiditis, optic neuritis and chronic anterior uveitis, disciform and interstitial keratitis, allergic corneal marginal ulcers, corneal injury from chemical radiation or thermal burns.
Ophthalmic steroid – antibiotic combined preparations
Dexamethasone is a synthetic glucocorticoid which decreases inflammation by inhibiting the migration of leukocytes and reversal of increased capillary permeability. It suppresses normal immune response.
Gatifloxacin inhibits bacterial DNA gyrase and Topoisomerase IV, the enzymes responsible for replication, transcription and repair of bacterial DNA.
Dosage & Administration
Instill 1-2 drops into the conjunctival sac 3 to 4 times daily.
This is contraindicated in epithelial herpes simplex keratitis (Dendritic keratitis), vaccinia, varicella, and in many other viral diseases of the conjunctiva and cornea. It is also contraindicated in mycobacterial infection of the eye, fungal diseases of ocular structures and in individuals hypersensitive to any of the components of the medication.
Mild burning, chemosis, redness may occur.
Pregnancy & Lactation
Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. Gatifloxacin + Dexamethasone should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Use in lactation: Caution should be exercised when Gatifloxacin + Dexamethasone is administered to a nursing mother.
Precautions & Warnings
For ophthalmic use only. If the product is used for 10 days or more, intraocular pressure should be monitored routinely.
Use in Special Populations
Use in children: Safety and effectiveness in pediatric patients have not been established.
Overdose through local administration is not known. In case of accidental oral intake, specific measures to reduce resorption should be taken. There is no specific antidote.
Store at room temperature. Protect from light. Close the bottle immediately after use. Do not use for longer than one month after opening the bottle.
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