PHENADRYL 100 ml Syrup

৳ 38

Sold By: JAHID PHARMA

In stock

Compare
SKU: 15315 Category: Tag:

Indications

Diphenhydramine is indicated for the treatment of followings:

  • Seasonal, perennial, vasomotor rhinitis
  • Urticaria, angioneurotic oedema, anaphylaxis
  • Pruiritic conditions
  • Premedication for emesis and motion sickness
  • Miscellaneous like meniere’s disease and parkinsonism

Therapeutic Class

Sedating Anti-histamine

Pharmacology

Diphenhydramine is an antihistamine with anticholinergic and sedative effects. It competes with histamine for H1-receptor sites on effector cells in the GI tract, blood vessels and respiratory tract.

Dosage & Administration

Adult-

  • Most allergic conditions: 25-50 mg three times a day with a further 50 mg at night.

Children-

  • 1 to 5 years of age: 5 mg i.e., 2.5 ml of elixir 4 times a day
  • More than 6 years of age: 10 mg i.e. 5 ml of elixir 4 times a day

Interaction

Diphenhydramine administration significantly reduces the absorption of the antituberculous agent para-aminosalicyclic acid (PAS) from the gastrointestinal tract. CNS depressants may potentiate the sedative action of Diphenhydramine. Anticholinergic drugs may potentiate Diphenhydramine’s anticholinergic side effects.

Contraindications

Known hypersensitivity to Diphenhydramine Hydrochloride, Ammonium chloride is contra-indicated in presence of impaired hepatic or renal function.

Side Effects

Side effect includes sedation, dizziness, tinnitus, fatigue, ataxia, blurred vision, diplopia, euphoria, and epigastric discomfort.

Pregnancy & Lactation

Category B: There are no adequate and well controlled studies in pregnant women using diphenhydramine hydrochloride. Therefore, diphenhydramine hydrochloride should be used in pregnancy only if clearly needed. Diphenhydramine hydrochloride has been reported to be excreted in breast milk and thus, use of diphenhydramine hydrochloride in lactating mother is not recommended.

Precautions & Warnings

Caution should be exercised with patients in whom drowsiness is undesirable e.g., drivers, machine operators. Concomitant consumption of alcohol or central nervous system (CNS) depressants will potentiate drowsiness.

Overdose Effects

Symptoms: Impaired consciousness; psychosis, seizures, antimuscarinic symptoms (e.g. mydriasis, tachycardia, tachyarrhythmias), resp failure, rhabdomyolysis; acute delirium with visual and auditory hallucination (topical).

Management: Supportive and symptomatic treatment. Convulsions and marked CNS stimulation may be treated with IV diazepam.

Storage Conditions

Store between 15-30° C. Protect from moisture.
Be the first to review “PHENADRYL 100 ml Syrup”

Your email address will not be published.

Reviews

There are no reviews yet.

Vendor Information

  • No ratings found yet!

Categories