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Sodiclor tablet Sodium Chloride BP 300 mg, 100’s pack
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Sodiclor 300 tablet: Each tablet contains 300 mg Sodium Chloride BP.
Pharmacodynamic properties: Sodium chloride is the principle salt involved in maintaining the
osmotic tension of blood and tissues, changes in osmotic tension influence the movement of
fluids and diffusion of salts in cellular tissue. Sodium Chloride tablet provides a source of
sodium where a deficiency exists.
Pharmacokinetic properties: Sodium chloride is readily absorbed from the gastro-intestinal
tract. It is present in all body fluids but specially in the extracellular fluid. The amount of sodium
lost (as sweat) is normally small. Osmotic balance is maintained by excretion of surplus
amounts in the urine.
Indications & Uses
• For the treatment and prophylaxis of Sodium Chloride deficiency
Dosage & Administration
It is important that the tablet should be swallowed whole with water (approx. 70 ml per tablet
where kidney function is normal to avoid hypernatraemia), and not chewed.
Adults: For prophylaxis 8-16 tablets per day. For treatment dosage to be adjusted to individual
needs up to a maximum of 40 tablets per day in case of severe salt depletion. For control of
muscle cramps during routine maintenance haemodialysis usually 20-32 tablets per dialysis.
In some cases of chronic renal salt-wasting up to 40 tablets per day may be required with
appropriate fluid intake.
Children: Dosage should be adjusted to individual needs.
Elderly: No special dosage adjustment.
Sodium Chloride is contra-indicated in any situation where salt retention is undesirable, such
as edema, heart disease, cardiac decompensation and primary or secondary aldosteronism;
or where therapy is being given to produce salt and water loss.
Special warnings and precautions for use
Use in Pregnancy: No additional precautions required.
Effects on ability to drive and use machines: Nil.
In hypertensive patients with chronic renal failure Sodium Chloride 300 mg tablet may tend to
impair the efficacy of antihypertensive drugs.
No side effects have been reported with Sodium Chloride 300 mg tablet at the recommended
Signs and symptoms: Excessive intake of sodium chloride can result in hypernatraemia.
Symptoms of hypernatraemia include restlessness, weakness, thirst, reduced salivation and
lachrymation, swollen tongue, flushing of the skin, pyrexia, dizziness, headache, oliguria,
hypertension, tachycardia, delirium, hyperpnoea and respiratory arrest.
Treatment: Treatment requires the use of sodium-free liquids and the cessation of excessive
sodium intake. In the event of a significant overdose serum sodium levels should be evaluated
as soon as possible and appropriate steps taken to correct any abnormalities. The use of a
loop diuretic e.g. frusemide (with potassium supplementation as required) may be appropriate
in severe cases of hypernatraemia. Levels should be monitored until they return to normal.
Store below 30°C in a dry place protected from light. Keep out of reach of Children.
Sodiclor 300 tablet: Each box contains 10 X 10 tablets in Alu-Alu blister pack
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