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Xylomet Plus Nasal Spray
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Sodium Cromoglicate + Xylometazoline Hydrochloride (2.6 mg+0.0325 mg)/spray 120 metered sprays
This Nasal Spray is indicated for the prophylaxis and treatment of allergic rhinitis (such as hay fever and perennial rhinitis) where this is accompanied by nasal congestion.
Mast Cell Stabiliser
Xylometazoline Hydrochloride is a sympathomimetic agent with alpha-adrenergic activity. It produces vasoconstriction thus reducing nasal congestion. This enables patients suffering from colds to breathe more easily through the nose.
Sodium Cromoglicate usually acts through a local effect on the nasal mucosa. It prevents release of the mediators of type-l allergic reactions, including histamine and slow reacting substance of anaphylaxis (SRS-A) from sensitized mast cells after the antigen-antibody union has taken place. The drug does not inhibit the binding of IgE and the specific antigen; instead it suppresses the release of substances (e.g., histamine, SRS-A) in response to this reaction. The drug also inhibits Type-III (late allergic, Arthers) reactions to a lesser extent.
Dosage & Administration
Adults (including the elderly) and children: One spray each nostril four times daily.
Contraindicated in patients with a known hypersensitivity to any ingredients of the preparation.
No serious side effects have been reported. Occasional irritation of the nasal mucosa may occur during the first day of use. In rare cases with Sodium Cromoglicate solutions alone wheezing and tightness of the chest has been reported. Because a lower dose of Xylometazoline is employed in this preparation it causes mild side effects such as nasal irritation, dryness of the nose, sneezing, headache, insomnia, drowsiness and palpitations.
Pregnancy & Lactation
As with all medicines, caution should be exercised during pregnancy especially during the first trimester.
Precautions & Warnings
The prolonged use or abuse of decongestants in general may lead to rebound congestion or drug induced rhinitis.
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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